Making his first Bills star, there's two things Thad Lewis plans to do: prepare hard and be confident.
"Any time you play football at this level, you have to be confident. If you second-guess yourself, you know those guys are going to take advantage of that so, going into the game, definitely going to be confident; be at home, definitely play a part, the crowd will be on my side this time, so looking forward to that," said Lewis.
A lot of times in this profession, you don't get an opportunity, and sometimes you'll never know, but now you have an opportunity and he'll go out there and be able to prove it, but he has a lot of people pulling for him," said head coach Doug Marrone.
Just as EJ Manuel began his career against a tough test against New England, Lewis faces a Bengals defense that scores well in statistical categories: 10th against the run; 11th against the pass - recording five interceptions through the season's first five games.
"I can't say what's going to be difficult. I just know the task. The task at hand is to go in there, prepare, and go out and, playmakers are out to make plays and play mistake-free football," Lewis said.
"We'll just have to do whatever we can to make him comfortable, do whatever we can as skill positions to make his job easier," said running back Fred Jackson.
Bringing a guy in from the outside probably would have been more difficult, but since he's been here, we've got reps with him. When we do RVAs, reps versus air, he's there throwing the ball to us too. Now its just a matter of listening to him in the huddle, understanding him, because the crowd gets loud," said wide receiver TJ Graham.
That crowd will get even louder if Lewis can have a good showing.